abstract：OBJECTIVES:To date, no worldwide studies have been conducted to estimate the biological age of five organs using clinical biomarkers that are associated with the aging status. Therefore, we conducted this study to develop the models for estimating the biological age of five organs (heart, lung, liver, pancreas, and kid...

journal_title：Maturitas

authors： Bae CY,Kang YG,Piao MH,Cho B,Cho KH,Park YK,Yu BY,Lee SW,Kim MJ,Lee SH,Kim YJ,Kim DH,Kim JS,Oh JE

更新日期：2013-07-01 00:00:00

abstract：:The Women's Health in the Lund Area (WHILA) project (n=6917) is a cohort study that started in 1995 and includes a postal questionnaire, physical examination, bone density measurement and blood laboratory analyses. Fracture data have been added, and in this report fracture risk and its association with sex hormones wa...

journal_title：Maturitas

authors： Moberg L,Nilsson PM,Samsioe G,Borgfeldt C

更新日期：2013-07-01 00:00:00

abstract：:Breast cancer is the most common female cancer in Spain. Its high prevalence, its high survival rate, and its incidence are the reasons treatment is increasingly sought for common problems by young women who have survived it. Besides the contraception and fertility issues, many breast cancer survivors develop sexual d...

journal_title：Maturitas

authors： Sánchez-Borrego R,Mendoza N,Beltrán E,Comino R,Allué J,Castelo-Branco C,Cornellana MJ,Duran M,Haya J,Juliá MD,Llaneza P,Navarro MC,Quereda F

更新日期：2013-07-01 00:00:00

abstract：:With ageing populations a major challenge is to maintain physical and cognitive function, quality of life and independence. The literature does not only indicate important gender differences in lifestyle behaviours, but also how these behaviours might affect health outcomes. The current review has a male perspective w...

journal_title：Maturitas

authors： Södergren M

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:Evaluate the association of self-reported vasomotor symptom (VMS) frequency with race/ethnicity among a diverse midlife US population and explore menopause symptom differences by dietary soy isoflavone (genistein+daidzein) consumption. STUDY DESIGN:Cross-sectional population-based study of peri- and postmen...

journal_title：Maturitas

authors： Reed SD,Lampe JW,Qu C,Gundersen G,Fuller S,Copeland WK,Newton KM

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To analyze the effects of statin use on bone turnover markers (BTM), in participants from a large population-based cohort. SUBJECTS AND METHODS:Cross-sectional study that included 2431 subjects (1401 women and 930 men) from the Camargo Cohort. We analyzed the differences in serum BTM between statin or non-st...

journal_title：Maturitas

authors： Hernández JL,Olmos JM,Romaña G,Martinez J,Castillo J,Yezerska I,Ramos C,González-Macías J

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:C-telopeptide crosslaps (CTX) and bone-specific alkaline phosphatase (BAP) do not provide sufficient sensitivity and specificity for diagnosis of osteoporosis. Cathepsin K (CatK), osteoprotegerin (OPG), and receptor activator of nuclear factor κB ligand (total (t) and soluble (s) RANKL) play an important rol...

journal_title：Maturitas

authors： Piatek S,Adolf D,Wex T,Halangk W,Klose S,Westphal S,Amthauer H,Winckler S

更新日期：2013-04-01 00:00:00

abstract：:Perimenopause is an imprecise period in woman over 40 years of age, which comprises the time between the moment that the first changes in the menstrual cycle appear and the year following the definitive cessation of the menses. Besides irregular bleeding, many women also complain of hot flashes and other characteristi...

journal_title：Maturitas

authors： Mendoza N,Sánchez-Borrego R,Cancelo MJ,Calvo A,Checa MA,Cortés J,Elorriaga MA,Díaz T,González JV,Lete I,Lobo P,Martínez-Astorquiza T,Nieto A,Olalla MA,Pérez-Campos E,Porqueras R,Quereda F,Salamanca A,De La Viuda E,S

更新日期：2013-03-01 00:00:00

abstract：:Within the last decade, breast cancer is increasingly understood as a heterogeneous disease comprising distinct entities that vary significantly with regard to molecular biology and clinical features. Despite impressive advances in the treatment of patients with breast cancer, not all patients derive equal benefits fr...

journal_title：Maturitas

authors： Liedtke C,Kiesel L

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Obesity, defined as an excess of total body fat, is a matter of concern all over the world, and its prevalence is still increasing among elderly people. OBJECTIVES:To examine whether sedentary behaviour (hours sitting per day) is associated with higher risk of central obesity, overweight-obesity and overf...

journal_title：Maturitas

authors： Gómez-Cabello A,Pedrero-Chamizo R,Olivares PR,Hernández-Perera R,Rodríguez-Marroyo JA,Mata E,Aznar S,Villa JG,Espino-Torón L,Gusi N,González-Gross M,Casajús JA,Ara I,Vicente-Rodríguez G,EXERNET Study Group.

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Depression is related to increased morbidity and mortality in the general population and among patients with coronary artery disease (CAD). The prevalence of major depression is two-times higher in women than men in the general population, but whether this pattern holds true in the CAD population has not bee...

journal_title：Maturitas

authors： Shanmugasegaram S,Russell KL,Kovacs AH,Stewart DE,Grace SL

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:To better define the longitudinal changes in renal function, to examine the associated risk factors, and to investigate whether there is an independent association of decline in renal function with presence of carotid plaque in a middle-aged and elderly healthy population. METHODS:245 healthy individuals (9...

journal_title：Maturitas

authors： Jiang S,Sun X,Gu H,Chen Y,Xi C,Qiao X,Chen X

更新日期：2012-11-01 00:00:00

abstract：:Ageing is accompanied with a progressive loss of muscle mass and force generating capacity. Ultimately, the muscle wasting and weakness may dramatically impact on mobility and the quality of life, where the elderly has increasing problems with performing activities of daily life, such as rising from a chair or climbin...

journal_title：Maturitas

authors： Degens H,Korhonen MT

更新日期：2012-11-01 00:00:00

abstract：:Treatments for osteoporosis over the last few decades have largely focused on antiresorptive agents that effectively prevent bone loss. Beginning with hormone therapy, a variety of new potent antiresorptive agents were developed, including oral and intravenous bisphosphonates, raloxifene and other selective estrogen r...

journal_title：Maturitas

authors： Lim V,Clarke BL

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:The activated vitamin D receptor (VDR) may have an important role in vascular health. The objective of this study was to determine whether there is an association between the expression of VDRs in coronary arteries and the extent of diet-induced atherosclerosis. METHODS:Utilizing a cohort of 39 postmenopausa...

journal_title：Maturitas

authors： Schnatz PF,Nudy M,O'Sullivan DM,Jiang X,Cline JM,Kaplan JR,Clarkson TB,Appt SE

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Studies assessing physical functionality with questions on ability to perform activities of daily living (ADLs) commonly make use of self- and informant-report measures. OBJECTIVES:Delineate the scenarios from which disagreement can arise and show evidence for the presence of disagreements when reporting on...

journal_title：Maturitas

authors： Siordia C

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Studies assessing physical functioning with the Physical Activity Scale for the Elderly (PASE) should be aware that the instrument may be age and culture insensitive. OBJECTIVES:To asses "classical" PASE scoring in a sample of aged (mean age 74) Mexican origin Latinos in the Southwestern United States and p...

journal_title：Maturitas

authors： Siordia C

更新日期：2012-08-01 00:00:00

abstract：:During the past 50 years, the prevalence of a cluster of chronic, inactivity-related diseases including obesity, insulin resistance and type 2 diabetes mellitus (T2DM), collectively referred to as 'metabolic syndrome' (MetS) has reached global epidemic proportions. Appropriate exercise training is a clinically proven,...

journal_title：Maturitas

authors： Bird SR,Hawley JA

更新日期：2012-08-01 00:00:00

abstract：:Gender inequalities in the financial resources in later life result from the combined effect of women's atypical life courses, which include interrupted employment records and periods of care provision, and the fact that pension systems have generally been slow in mitigating 'diversions' from continuous and full-time ...

journal_title：Maturitas

authors： Vlachantoni A

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the putative changes in serum angiotensinase activities (aminopeptidase N, APN; aminopeptidase B, APB; aminopeptidase A, APA; aspartyl aminopeptidase, ASAP) involved in the renin-angiotensin system (RAS) in women with breast cancer treated or not with a neoadjuvant thera...

journal_title：Maturitas

authors： Ramírez-Expósito MJ,Carrera-González Mdel P,Mayas MD,Dueñas B,Martínez-Ferrol J,Martínez-Martos JM

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:There is a global trend of increasing numbers of older women in the workforce. However, limited information is available regarding the relationship between the menopause transition and work, especially in developing countries. The objectives of this study were to investigate the relationship between experien...

journal_title：Maturitas

authors： Hammam RA,Abbas RA,Hunter MS

更新日期：2012-03-01 00:00:00

abstract：:As increasing numbers of individuals reach very advanced age, it is important to understand the influence of modifiable lifestyle factors such as diet and nutrition on both the achievement of exceptional longevity as well as the maintenance of optimal functional capacity. This includes determining the most appropriate...

journal_title：Maturitas

authors： Hausman DB,Fischer JG,Johnson MA

更新日期：2012-03-01 00:00:00

abstract：:Osteoarthritis (OA) is a common age-related disease that affects the tissues of the synovial joint, leading to loss of function and pain. It impacts on both patient morbidity and mortality. It is a complex, polygenic disease that lacks any large-effect susceptibility loci. Instead, OA susceptibility alleles individual...

journal_title：Maturitas

authors： Reynard LN,Loughlin J

更新日期：2012-03-01 00:00:00

abstract：:Hot flashes are a common complaint among women as they transition through menopause. This article reviews the evidence of lifestyle alterations for the amelioration of hot flashes including obesity, exercise, smoking, relaxation techniques, and acupuncture. Further randomized controlled trials regarding these lifestyl...

journal_title：Maturitas

authors： Fisher TE,Chervenak JL

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:This study examined factors associated with self-reported physical and mental health, focusing on caregiving status and the availability of social supports and financial resources. METHODS:Two bivariate analyses were performed to examine the sociodemographic characteristics as well as perceived health outco...

journal_title：Maturitas

authors： Ahn S,Hochhalter AK,Moudouni DK,Smith ML,Ory MG

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To test whether a synonymous single nucleotide polymorphism (A→G; rs700518) in the CYP19A1 gene, which encodes the enzyme aromatase, is associated with an increased risk for hypertension of midlife women. METHODS:In a cross-sectional study, 639 midlife women were recruited. Eligible women had their blood pre...

journal_title：Maturitas

authors： Ziv-Gal A,Gallicchio L,Miller SR,Zacur HA,Flaws JA

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Our pilot study tested the efficacy, acceptability and tolerability of DHA supplementation in addition to calcium and vitamin D in individuals with osteopenia. STUDY DESIGN:40 participants were randomised to either algal oil containing 400mg docosahexanoic acid (DHA) daily or placebo. All participants recei...

journal_title：Maturitas

authors： Vanlint SJ,Ried K

更新日期：2012-01-01 00:00:00

abstract：:Stroke represents one of the most important menaces to public health. A number of modifiable and non-modifiable risk factors have been identified and studied in detail; among those, obesity, the new world epidemic, seems to be one of the most important in terms of prevention. The discovery of the secretory role of the...

journal_title：Maturitas

authors： Savopoulos C,Michalakis K,Apostolopoulou M,Miras A,Hatzitolios A

更新日期：2011-12-01 00:00:00

abstract：:The increased risk of breast cancer recently observed with some specific estro-progestin associations has raised concerns about the harmful effects of menopausal hormone replacement therapy (HRT). It has been proposed that phytoestrogens (PEs), which have a similar chemical structure to estrogens, could be used as HRT...

journal_title：Maturitas

authors： This P,de Cremoux P,Leclercq G,Jacquot Y

更新日期：2011-11-01 00:00:00

abstract：:Premature ejaculation (PE) is the most common male sexual complaint, and may exert a profound negative impact on the man's life and partnership. Using currently available treatment alternatives (e.g., selective serotonin uptake inhibitor, agents acting locally on the penis), PE can be treated in most, but not all pati...

journal_title：Maturitas

authors： Andersson KE,Abdel-Hamid IA

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:To describe the characteristics, metabolic control and health-related quality of life (HRQL) of type 2 diabetes mellitus (T2DM) geriatric patients. STUDY DESIGN:Cross-sectional descriptive study of consecutive patients attended at a geriatric outpatient clinic in a tertiary hospital over three months. Socio...

journal_title：Maturitas

authors： Rodríguez-Pascual C,Rodriguez-Justo S,García-Villar E,Narro-Vidal M,Torrente-Carballido M,Paredes-Galan E

更新日期：2011-08-01 00:00:00

abstract：:Cardiovascular disease is the leading determinant of mortality and morbidity in women. Functional foods are attracting interest as potential regulators of the susceptibility to disease. Supported by epidemiological evidence, chocolate has emerged as a possible modulator of cardiovascular risk. Chocolate, or cocoa as t...

journal_title：Maturitas

authors： Fernández-Murga L,Tarín JJ,García-Perez MA,Cano A

更新日期：2011-08-01 00:00:00

abstract：:Ageing of human skin may result from both the passage of time (intrinsic ageing) and from cumulative exposure to external influences (extrinsic ageing) such as ultraviolet radiation (UVR) which promote wrinkle formation and loss of tissue elasticity. Whilst both ageing processes are associated with phenotypic changes ...

journal_title：Maturitas

authors： Naylor EC,Watson RE,Sherratt MJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To examine whether physical activity during the last five years is related to later breast mammographic density in postmenopausal Greek women. METHODS:We designed a cross-sectional study in 724 women, of ages 45-67 years. An interview-administered questionnaire was used to obtain information on duration and ...

journal_title：Maturitas

authors： Marmara EA,Papacharalambous XN,Kouloulias VE,Maridaki DM,Baltopoulos JP

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To assess predictors of sexual function in mid-aged women. METHODS:We analyzed data of 262 healthy sexually active women (40-59 years) who filled out the Female Sexual Functioning Index (FSFI), the Menopause Rating Scale (MRS) and a general questionnaire containing female/partner data. Correlations between t...

journal_title：Maturitas

authors： Chedraui P,Pérez-López FR,Mezones-Holguin E,San Miguel G,Avila C,Collaborative Group for Research of the Climacteric in Latin America (REDLINC).

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The role of endogenous testosterone in the pathogenesis of type 2 diabetes mellitus remains vague. We investigated whether associations between endogenous testosterone and diabetes prevalence in men could be partially explained by modifiable risk factors. STUDY DESIGN:A random population-based cross-sectiona...

journal_title：Maturitas

authors： Atlantis E,Lange K,Martin S,Haren MT,Taylor A,O'Loughlin PD,Marshall V,Wittert GA

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:Osteoporosis and its consequent fractures is a major public health problem. AIM:To formulate a position statement on the use of bone densitometry in screening postmenopausal women for osteoporosis and in their management. MATERIALS AND METHODS:Literature review and consensus of expert opinion. RESULTS A...

journal_title：Maturitas

authors： Brincat M,Calleja-Agius J,Erel CT,Gambacciani M,Lambrinoudaki I,Moen MH,Schenck-Gustafsson K,Tremollieres F,Vujovic S,Rees M,Rozenberg S,EMAS.

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To examine the prevalence and correlates of foot problems in older women over a 6-year period. STUDY DESIGN:Women aged 70-75 years who participated in the Australian Longitudinal Study on Women's Health completed a postal questionnaire incorporating questions relating to demographics, major medical condition...

journal_title：Maturitas

authors： Menz HB,Barr EL,Brown WJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The higher risk of women developing autoimmune diseases suggests that immune system is mediated by sex steroids. OBJECTIVE:To review the effects of aging and menopause in immune system. METHODS:A systematic review of in vitro, animal and human studies involving aging and menopause and immune system was car...

journal_title：Maturitas

authors： Gameiro CM,Romão F,Castelo-Branco C

更新日期：2010-12-01 00:00:00

abstract：:The specific profile of estrogens on cardiovascular risk, with limiting action on atherogenesis but a less clear protection on cardiovascular episodes, might be improved by other agonists of the estrogen receptor, such as isoflavones. By using a systematic search based on the electronic Medline database plus a hand-se...

journal_title：Maturitas

authors： Cano A,García-Pérez MA,Tarín JJ

更新日期：2010-11-01 00:00:00